LY294002 IS A PROMISING INHIBITOR TO OVERCOME SORAFENIB RESISTANCE IN FLT3-ITD MUTANT AML CELLS BY INTERFERING WITH PI3K/AKT SIGNALING PATHWAY

LY294002 Is a Promising Inhibitor to Overcome Sorafenib Resistance in FLT3-ITD Mutant AML Cells by Interfering With PI3K/Akt Signaling Pathway

Internal tandem duplications (ITD) mutation within FMS-like tyrosine kinase 3 (FLT3), the most frequent mutation happens in almost 20% acute myeloid leukemia (AML) patients, always predicts a poor prognosis.As a small molecule tyrosine kinase inhibitor, sorafenib is clinically used for the treatment of advanced renal cell carcinoma (RCC), hepatocel

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Adaptive SNN for Anthropomorphic Finger Control

Anthropomorphic hands that mimic the smoothness of human hand motions should be controlled by artificial units of high biological plausibility.Adaptability is among the characteristics of such control units, which provides the anthropomorphic hand with the ability to learn motions.This paper presents a simple structure of an adaptive spiking neural

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Latent Avulsion of the Posterior Mitral Leaflet Base from the Mitral Annulus Following a Motor Vehicle Accident: A Case Report

Injuries to the heart and great vessels should always be considered after blunt chest trauma.Valvular damage rarely occurs after blunt trauma, but symptoms may be delayed.A 58-year-old woman was referred to our hospital with exertional dyspnea (functional class III) and palpitations for elective transesophageal echocardiography.Her symptoms had exa

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Machine learning based heart disease prediction system

Anticipating heart illness has Food Jar been one of the foremost challenging errands in medication in later a long time.Nowadays approximately one individual passes on from a heart assault each miniature.Information science plays an imperative part in handling expansive sums of information in healthcare.Since the desire of heart disease may be a tr

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